Plcz1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPlcz1 ELISA Kit for Rat(Rattus norvegicus)

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Plcz1 (Gene name),

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 (Protein name ), PLCZ1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Plcz1;

Protein name:

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1;

Alternative:

Phospholipase C-zeta-1(PLC-zeta-1);Phosphoinositide phospholipase C-zeta-1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts via its C2 domain with PtdIns(3)P and, to a lesser extent, PtdIns(5)P in vitro.

Function:

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

Subcellular Location:

Nucleus Cytoplasm perinuclear region Exhibits alternative cytoplasmic/nuclear localization during development. Translocates from the pronucleus into cytoplasm upon nuclear envelope breakdown for mitosis and localizes again to the pronucleus at interphase following meiosis and mitosis.

Protein Attributes:

Sequence length:

645

Sequence:

50:

100:

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250:

300:

350:

400:

450:

500:

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600:

645:

NELLGQYTLP | VLCMNKGYRR | VPLFSKSGAN | LEPSSLFIYV | WYYRE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:497197

UniGene:

Rn.123184

STRING:

10116.ENSRNOP00000011376

String:

Q5FX52

Pfam:

PF00168

Uniprot:

Q5FX52

FOR

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

E15484h

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

E15484c

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

E15484m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

E15484r

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

E15484b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

U15484m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

U15484h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

U15484r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

U15484c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

U15484b

Price:

Please sign in first.

MSDS:

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Packing:

96T

Polyclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

P15484Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

P15484Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Cat.:

P15484Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

Protein for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Saunders C.M.
Submitted (2005-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Testis.
2.

"Difference in Ca2+ oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, between mouse, rat, human, and medaka fish."
Ito M. , Shikano T. , Oda S. , Horiguchi T. , Tanimoto S. , Awaji T. , Mitani H. , Miyazaki S.
Biol. Reprod.78:1081-1090(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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